Amount changed equals the equivalent stat up/down pill. Plus this gambling machine is simple and quick, unlike the Slot Machines of old. Stat Down becomes Stat Up. UNLOCK: Unlock this trinket by collecting three of the following in the same run: Magic 8 Ball, Tiny Planet, Crystal Ball, Star of Bethlehem or any of the Astrology-related items (e.g. Function: Gives Flight, +2 Soul Hearts, Holding down the fire button for 2.35 seconds charges a beam that deals 15 ticks of your tear damage, Unlock Condition: Defeat Mother as Bethany. in an Angel room, this will spawn 2 Angel room items), Starts with 0 charge and requires 12 charges to use, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Eden, Every 6-7 rooms Acid Baby will drop a random pill, Every time you use a pill, Acid Baby will deal 10 damage to all enemies and poison them for 6-7 ticks, REPENTANCE - Poison effect is stronger, but Acid Baby's pill drop rate has been reduced to every 6-7 rooms (previously every 2-3 rooms), A familiar fairy that will float around the room and highlight the location of any secret room doors, tinted rocks or trapdoors under rocks, Upon entering a new room, if there is an undiscovered secret room or tinted rock, it will move directly to the point of interest, otherwise it will just randomly fly around the room, For every empty red heart container, Isaac gains Damage Up and his body increases in size, Only works on full hearts - damage does not change if Isaac is missing 1/2 of a heart in one container, Healing empty red heart containers will remove the damage increases, Has no effect for The Lost and ?? Based on the Steam Workshop mod created by Jean-Alphonse, UNLOCK: Unlock this item by opening 20 locked chests, *, mr me!, Mr Meeseeks, rick and morty, brown, chest, szechuan sauce, mister me, Grants a prism orbital with a large orbital radius, Isaac's tears that pass through the prism split into four multi-colored tears, Does not deal contact damage to enemies that it passes over, Added as part of the Afterbirth+ Booster Pack #3. THEGHOST. Get hit by one enemy that does damage and you die. Of all the tear replacer effects, I find that this isn't the strongest one overall and it's a bit tough to use, plus it overrides literally everything else. Has a high chance to give you the effect of a random Mom item every room, UNLOCK: Unlock this trinket by defeating Isaac, ?? Keys and bombs are equal to 3 coins for deciding which to give, Item Pool: Boss Room, Golden Chest, Crane Game, Grants a large orbital that rotates around Isaac, When the orbital takes a few hits, they split into two smaller ones, After the smaller orbitals take another hit, they explode into 2 blue spiders, This item will respawn after a period of time, UNLOCK: Unlock this item by defeating Mother in the Corpse II as Lazarus, Your bombs now explode and fire 4 Brimstone lasers in all cardinal directions, Each brimstone laser deals 8 damage per tick for 13 total hits, UNLOCK: Unlock this item by killing Hornfel before he can escape after breaking his minecart, Item Pool: Devil Room, Bomb Beggar, Greed Mode Devil Room, Active items no longer charge up as normal from clearing rooms, Enemies taking damage now charges your item instead. Unlocked from the 'Once more with the feeling!' Finding all the puzzle pieces will help you to reveal the final secret, unlocking the hidden character 'The Lost', If held when you touch the chest after the Satan or Isaac fight and you don't have the relevant item to go to the next floor (Polaroid or Negative), you have a small chance to be taken there anyway, UNLOCK: Unlock this item by beating the Chest with Eden, 80% of heart drops are replaced with keys, Hearts turn into black hearts where possible. * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, The effect triggers again 30 seconds after use and again 60 seconds after use, Something's wrong - Spawns a pool of black creep beneath Isaac, Vurp! (Blue baby), *, dead, blue, face, fates reward, fate reward, A familiar chest that follows Isaac and has a 25% chance to drop a pickup after clearing a room, Possible drops include hearts, coins, bombs, key, pills, card, runes, batteries, trinket, UNLOCK: Unlock this item by beating Greed Mode with Isaac, Item Pool: Item Room, Greed Mode Item Room, Beggar, An orbital angel which does 7 contact damage per tick and blocks shots, The angel will attract bullets towards it and block them, Sworn Protector will drop an eternal heart if it blocks 10 shots in one room. Can cause white poops through other item effects such as A Card Against Humanity or Re-Lax pills. white, brown, underwear, moms bra, mom bra, Causes an explosion near Isaac which takes away half a heart and does 40 damage all enemies in close proximity, REPENTANCE - Kamikaze now has increased blast damage and radius. It rerolls enemies and pickups it comes into contact with, then despawns. Despite my best efforts, it can only load simple mods that consist of scripts, no mods that contain "resources" from my testing (External Item Descriptions does not work, much to my dismay). After killing a 15 enemies, Blood Puppy transforms into an aggressive version that will also attack Isaac by charging at him. Creator Edmund McMillen called it the "best version of Isaac". REPENTANCE - White poop from Hallowed Ground is now more durable, similar to golden poop. Pressing the bomb button will put the next poop into the 'Hold' jar. Here is the requirements for getting 1001% completion rate in Binding of Isaac. One exception to this is if you are playing as Lazarus or have Lazarus' Rags - you will respawn in the same room and get the kill, Plan C is 5 times rarer than other items in the same item pool, making it less likely to appear, UNLOCK: Unlock this item by defeating Greedier Mode with Lazarus, Item Pool: Shop, Devil Room, Curse Room, Red Chest, Demon Beggar, When used, the D1 duplicates 1 random pickup in the current room. If the enemy dies while in this state they will drop 1-4 coins, Rainbow poop Dips charm enemies and have a chance to spawn 1/2 a red heart on death. As you slide more elements, the others will be eliminated and the others will be rolled softly 5 keys = 100% chance. When used, fills the entire room with poop! green, red, bloody, A familiar that follows Isaac and leaves blood creep on the floor as it floats, hurting enemies that walk over it for 2 damage per tick, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, bloody, red, pants, under wear, pink, knickers, moms underwear, mom underwear, REPENTANCE - Touching enemies deals 12 damage to them, Item Pool: Boss Room, Challenge Room, Mom's Chest, * dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, high, shoe, moms heels, mom heels, Drops a random heart on the floor when picked up, * moms lipstick, mom lipstick, dungeon room, blood challenge room, arena pool, boss room pool, boss room item, red, grey, gray, UNLOCK: Unlock this item by beating Mom's Heart 4 times, Gives Isaac angel wings for the current room, allowing him to fly, Instantly kills the Mom's Foot, Mom's Heart and It Lives boss fights, If used during the Satan fight, The Bible will instantly kill Isaac, Counts as 1 of 3 angel items needed towards the Seraphim transformation, REPENTANCE - Reduced to 4 room recharge time, * library pool, library room, book room pool, angel room pool, god room pool, angel room item, jailbird paper washington, nc; axe throwing augusta maine; eric pospisil age; david dayan fisher binding of isaac: repentance unlock guide. The charge time is based on your tears stat. ?, Satan and The Lamb as Tainted Isaac, Every time you enter a brand new room, you have a chance to get a random one-time use Dice (e.g. * shop room pool, shop item pool, the lost item pool, white, Causes Isaac's head to detach and orbit his body, blocking shots and dealing 7 contact damage per tick, BFFs will cause the Guillotine head to do double damage (14 damage per tick), Tears are still fired from Isaac's head but the hitbox remains around his body, UNLOCK: Unlock this item by beating the Isaac boss with Judas, * item room, treasure room, item room pool, chop, head, silver, metal, Gives Isaac an orbital ball of bandages that deals 7 contact damage per tick and blocks enemy shots, Collecting a second Ball of Bandages in the run turns the orbital into a pink head that shoots tears that deal 7 damage each and have a chance to charm enemies, Getting a third Ball of Bandages will transform the head into bandage girl which will chase enemies dealing 3.5 contact damage per tick while firing charm tears, A fourth Ball of Bandages will make the Bandage Girl bigger and stronger, making her deal 5.5 damage per tick instead, Any further Ball of Bandages will repeat the cycle, Increases the chance of champion enemies appearing by 15%, Doesn't affect the chance for champion bosses to spawn, * shop room pool, shop item pool, red, croissant, crescent, Bombs now become poop bombs, which deal 10 damage to all enemies in the room and daze them for a short period of time, Butt Bombs heal the poop bosses (Dingle, Dangle, Brownie) by 25% of their max HP, * boss rush pool, boss rush room, item room, treasure room, item room pool, poop, face, brown, If Isaac stands still and stops shooting for a second, he turns to stone, making him invincible until he moves/shoots again, Using bombs or your active item will remove the invicibility as well, This item is a reference to the Tanuki suit in Super Mario 3, * item room, treasure room, item room pool, raccoon, green, Spawns 2-5 friendly attack spiders every time you take damage, REPENTANCE - Buffed, used to spawn 1-2 spiders, * item room, treasure room, item room pool, the lost item pool, purple, blue, heart, cute spider baby, When Isaac dies, he has a 50% chance to resurrect with 1/2 a heart, * curse room pool, red chest pool, red chest item pool, devil pool, devil room pool, devil deal, I want to add that almost EVERY tainted character have something interesting added to game after beating mega satan. * boss room pool, boss room item, brown, leather, bag, sack, golden chest pool, gold chest pool, Gives 3-6 blue attack flies when picked up, Item Pool: Boss Room, Challenge Room, Gold/Stone Chest, Mom's Chest, * dungeon room, blood challenge room, arena pool, boss room pool, boss room item, panties, on enemy death, on room clear, on damage taken etc. When used, this card drops all of your hearts (including non-red hearts), coins, keys and bombs on the floor, This effect is done in the most efficient way possible - e.g. Gives a small chance when entering a room for enemies to be petrified for 4 seconds. During this time he can walk over enemies to mark them for death. Corpse II drops same as Womb II, UNLOCK: Unlock this item by beating the Dark Room with Lazarus, * red chest pool, red chest item pool, shop room pool, shop item pool, blue box, pandoras box, When used, turns Isaac invincible and gains +0.28 speed for a 5 seconds, You cannot fire tears while the stump is active, Very similar to the My Little Unicorn item but does not deal contact damage, When used with Mom's Knife, you can still deal contact damage but will be unable to change the way the knife faces while the effect is active, * item room, treasure room, item room pool, white, lump, grey, gray, blob, While in a hostile room your speed raises at a rate of +0.065 per game tick, When you hit a speed stat of 2.0, Isaac will gain an invincibility effect for 5 seconds, increasing speed and allowing him to run into enemies to deal 40 contact damage per hit, The time it takes for the effect to activate becomes shorter with a higher base Speed stat, * astrology, astronomy, item room, treasure room, item room pool, blue, glow, circle, horns, Gives huge horns which stick out, allowing you to deal 18 contact damage if you hit something with enough speed, Will not deal contact damage unless you are moving fast enough (at least 0.8 speed), REPENTANCE - Aries now prevents receiving contact damage if ramming and killing enemies at full speed, * astrology, astronomy, item room, treasure room, item room pool, black, blue, cyan, glow, After getting hit once, you gain a damage reduction for the rest of the room similar to The Wafer item (-50% damage taken), * astrology, astronomy, item room, treasure room, item room pool, cyan, black, the lost item pool, * , the lost item pool, head, bone, grey, gray, Gives Isaac a higher chance to find pills, Gives Isaac a higher chance to find Tarot cards after clearing a room or from chests, After clearing a room, you have a chance to heal for half a red heart, *, the lost item pool, silver, metal, grey, gray, isaacs fork, When taking damage, Isaac has a chance to deal damage to the entire room in a Necronomicon style effect, The chance to damage enemies is affected by your luck stat and at +50 or more Luck it will activate 50% of the time, * , the lost item pool, pink, purple, paper, red, Everytime you pick up a penny, you have a 25% chance to spawn a red heart on the floor, UNLOCK: Unlock this item by beating the Chest with Samson, * , the lost item pool, red, coin, cent, money, Everytime you pick up a coin, you have a 25% chance to spawn a bomb on the floor, UNLOCK: Unlock this item by beating Challenge #13 (Beans! ?, Satan and The Lamb as Tainted Apollyon, Gives you a red attack fly, that will charge at enemies in the same direction you are shooting, Deals damage equal to your current tear damage, Stops charging once it hits an enemy and returns to Isaac's side, UNLOCK: Unlock this trinket by defeating Mother as Tainted Apollyon, Gives a 33% chance to spawn an extra blind pedestal item in all future item rooms. There are some 300 gameplay changes, according to YouTuber IsaacGuru. The poison deals your tear damage per tick, for 2 ticks, Has no effect on Lilith, as she cannot fire tears, While firing tears constantly for 7.5 seconds, you spawn a poop cloud, which deals periodic damage to any enemies which come near it, The cloud deals damage equal to your base tear damage per tick, roughly 5 times per second, Clouds last 15 seconds before disappearing, The cloud can be pushed slightly by firing tears at it, Upon taking damage, Isaac starts to bleed, leaving a trail of blood and spraying blood tears everywhere which deal damage to nearby enemies, While bleeding, Isaac takes damage every 30 seconds, The blood sprays in the direction you are current firing, or just randomly near Isaac if not shooting your tears, The blood spray scales with your current tear damage and any future damage increases, This effect lasts until you pick up a red heart, Upon taking damage, this item gives a 25% chance to drop a full red heart, REPENTANCE - This entire item has been reworked, Enemy bullets have a 25% chance to be deflected back at the enemy, which will hurt them and apply the concussive status effect, causing it to be stunned for a few seconds, Every 20th tear fired will also fire a golden coin tear at the same time. 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